:root{color-scheme:light;--ink:#20262d;--muted:#5b6470;--line:#dce1e6;--surface:#fff;--ground:#f6f7f9;--blue:#165ab8;--tint:#edf3fc;--caution:#805000;--caution-bg:#fff5df;font-family:-apple-system,BlinkMacSystemFont,"Segoe UI",sans-serif}
*{box-sizing:border-box}html{scroll-behavior:smooth;scroll-padding-top:24px}body{margin:0;background:var(--ground);color:var(--ink);font-size:15px;line-height:1.55;-webkit-font-smoothing:antialiased}h1,h2,h3,p{margin:0}h1{font-size:30px;letter-spacing:-.025em;line-height:1.2;text-wrap:balance}h2{font-size:19px}p{max-width:74ch}a{color:var(--blue);text-underline-offset:3px}button,select,input{font:inherit;color:inherit}a,button,summary,input,select{touch-action:manipulation}summary,button{cursor:pointer}a:focus-visible,button:focus-visible,summary:focus-visible,input:focus-visible,select:focus-visible{outline:2px solid var(--blue);outline-offset:3px}::selection{background:#cddff8;color:#173756}input{caret-color:var(--blue)}[hidden]{display:none!important}.skip{position:fixed;top:-100px;left:16px;z-index:3;background:white;padding:12px}.skip:focus{top:12px}
header{background:var(--surface);border-bottom:1px solid var(--line)}.top{max-width:1060px;margin:auto;padding:18px 28px;display:flex;align-items:center;justify-content:space-between;gap:20px}.brand{font-size:17px;font-weight:650;color:var(--ink);text-decoration:none}.brand span{display:block;font-size:12px;font-weight:400;color:var(--muted)}nav{display:flex;gap:24px;align-items:center}nav a{font-size:13px;text-decoration:none;padding:8px 0;border-bottom:2px solid transparent}nav a[aria-current]{border-bottom-color:var(--blue);font-weight:650}nav a:hover{text-decoration:underline}
main,footer{max-width:1060px;margin:auto;padding:30px 28px}.intro{margin-bottom:24px}.intro p{margin-top:10px;color:var(--muted);font-size:14px}.review{border-bottom:1px solid var(--line);padding:0 0 4px}.review>summary{padding:13px 0;font-size:13px;color:var(--blue);font-weight:550}.review .reading{padding:4px 0 18px;font-size:13px;max-width:78ch}.reading p+p{margin-top:13px}.reading ul{padding-left:22px;margin:14px 0}.reading li+li{margin-top:9px}.clinical{margin-top:30px}.citation{font-size:12px;text-decoration:none;border-bottom:1px dotted #a0badd;margin-left:4px}.citation:hover{background:var(--tint)}
.filters{display:grid;grid-template-columns:minmax(0,1fr) 235px;gap:18px;margin:26px 0 12px}label{display:block;font-size:12px;font-weight:600;margin-bottom:7px}input,select{width:100%;border:1px solid #bcc5cf;border-radius:8px;background:white;min-height:44px;padding:10px 12px;font-size:14px}input::placeholder{color:var(--muted);opacity:1}select{padding-right:26px}.result-line{font-size:12px;color:var(--muted);margin-bottom:10px}
.entry{border-bottom:1px solid var(--line);background:var(--surface)}.entry:first-child{border-top:1px solid var(--line)}.entry>summary{list-style:none;display:grid;grid-template-columns:minmax(0,1fr) auto 14px;gap:14px;align-items:start;padding:18px 20px}.entry>summary::-webkit-details-marker{display:none}.entry>summary:after{content:"";width:7px;height:7px;border-right:1.5px solid currentColor;border-bottom:1.5px solid currentColor;transform:rotate(45deg);margin-top:6px;transition:transform .16s ease-out;color:var(--muted)}.entry[open]>summary:after{transform:rotate(225deg);margin-top:10px}.entry>summary:hover{background:#f0f4f9}.entry>summary:focus-visible{outline-offset:-3px}.entry strong{font-size:14px;font-weight:650;display:block}.entry .ingredient-copy{display:block;margin-top:4px;font-size:13px;color:var(--muted);max-width:74ch;font-variant-numeric:tabular-nums}.entry-body{padding:0 20px 18px;font-size:13px}.entry-body p+p{margin-top:9px}.metadata{color:var(--muted);font-size:11px}.entry-body .sources{margin-top:9px}.entry-body .sources .citation:first-child{margin-left:0}.empty{padding:32px 0}.empty p{margin-top:10px;color:var(--muted)}button{border:1px solid #bcc5cf;background:white;border-radius:8px;padding:10px 14px;font-size:13px;margin-top:16px}button:hover{background:var(--tint)}
footer{padding-top:0;font-size:12px}.footer-links{border-top:1px solid var(--line);padding-top:20px;display:flex;flex-wrap:wrap;gap:14px 24px}.footer-note{color:var(--muted);margin-top:14px}#app-identity{font-size:11px;color:var(--muted);margin-top:5px}#references{margin-top:20px}#references>summary{font-size:13px;color:var(--blue);font-weight:550;padding:10px 0}.ref-list{padding:0;list-style:none;font-size:12px;line-height:1.65}.ref-list li{margin-top:16px;padding:8px 10px 8px 28px;text-indent:-18px;max-width:95ch;overflow-wrap:anywhere;border-radius:8px}.ref-list li:target,.ref-list li.selected{background:var(--tint)}.ref-list .locator{display:block;font-size:11px;color:var(--muted);text-indent:0;margin-top:4px}.noscript{margin:20px auto;max-width:75ch;padding:20px}
.filters{display:block;margin:26px 0 12px}.search-field{max-width:640px}.group-choices{display:flex;flex-wrap:wrap;gap:8px;margin-top:18px}.group-choices button{margin:0;min-height:42px;padding:9px 14px}.group-choices button[aria-pressed=true]{color:#124a94;background:var(--tint);border-color:#8eb4e5;font-weight:600}.catalog-section+.catalog-section{margin-top:32px}.catalog-heading{padding:14px 0}.catalog-heading h2{font-size:19px;letter-spacing:-.015em}.catalog-heading p{font-size:13px;color:var(--muted);margin-top:4px}.group-guidance{font-size:13px;line-height:1.65;margin:18px 0;max-width:76ch}.product-context{border-top:1px solid var(--line);padding-top:14px;margin-top:16px}.product-context h3{font-size:13px;margin-bottom:8px}.product-context p{font-size:13px}.product-context .study-context{color:var(--muted);font-size:12px}.exposure-snapshot{margin:14px 0;display:grid;grid-template-columns:1fr 1fr;gap:18px}.exposure-snapshot dt{font-size:12px;color:var(--muted)}.exposure-snapshot dd{margin:4px 0 0;font-size:16px;font-weight:600;font-variant-numeric:tabular-nums}.metric-detail{display:block;color:var(--muted);font-size:12px;font-weight:400}.evidence-action{display:inline-block;margin-top:12px;padding:8px 0;font-size:13px;font-weight:600}.catalog-section>.entry:nth-child(2){border-top:1px solid var(--line)}
@media(max-width:760px){.top,main,footer{padding-left:20px;padding-right:20px}.top{flex-wrap:wrap;gap:12px}nav{gap:22px}main{padding-top:26px}h1{font-size:25px}.filters{grid-template-columns:1fr;gap:12px}.entry>summary{padding:16px 14px;gap:10px;grid-template-columns:minmax(0,1fr) 12px}.entry>summary:after{grid-column:2;grid-row:1}.entry .entry-body{padding:0 14px 16px}.entry strong{font-size:14px}.entry .ingredient-copy{font-size:13px}.footer-links{flex-direction:column;gap:12px}.review .reading{font-size:13px}input{font-size:16px}.group-choices{display:grid;grid-template-columns:1fr 1fr}.group-choices button{padding:9px 7px;font-size:12px}.exposure-snapshot{grid-template-columns:1fr;gap:12px}}
@media(prefers-reduced-motion:reduce){html{scroll-behavior:auto}.entry>summary:after{transition:none}}@media print{.filters,nav,.skip,.result-line,.empty{display:none}body{background:white}main,footer{max-width:none;padding:12px}.entry>summary{break-inside:avoid}.entry{break-inside:avoid}.ref-list li{break-inside:avoid}}
.sr-only{position:absolute;width:1px;height:1px;padding:0;margin:-1px;overflow:hidden;clip-path:inset(50%);white-space:nowrap;border:0}
.intro{margin-bottom:20px}.intro p{font-size:15px;margin-top:8px}
.filters{margin:20px 0 16px}.search-field{max-width:none}.group-choices{margin-top:12px}.group-choices button{min-height:44px}
.entry>summary{grid-template-columns:minmax(0,1fr) 12px;padding:15px 18px;align-items:center}.entry>summary:after{margin-top:0}.entry[open]>summary:after{margin-top:4px}.entry .ingredient-copy{font-size:12px;line-height:1.5}.entry-body{padding:0 18px 18px;font-size:14px}.entry[open]{outline:1px solid #c8d5e4;outline-offset:-1px}.entry[open]>summary{padding-bottom:18px}.restriction-hint{display:block;font-size:12px;color:#a22c29;margin-top:6px;font-weight:550}
.practical{padding:0 0 14px;max-width:75ch}.practical h3{font-size:15px;line-height:1.4;margin-bottom:10px;font-weight:650}.practical p{font-size:14px;line-height:1.65}.restriction h3{color:#a22c29}.practical p+p{margin-top:9px}.label-link{display:inline-block;font-size:12px;margin:0 0 14px}.supporting{border-top:1px solid var(--line)}.supporting>summary{padding:12px 0;font-size:13px;font-weight:550;color:var(--blue)}.supporting-body{padding:0 0 16px;max-width:75ch;font-size:13px;line-height:1.65}.supporting-body p+p{margin-top:10px}.evidence-action{display:block;font-size:13px;padding:10px 0;margin:0 0 4px;font-weight:550}.entry-body .evidence-action+.supporting{margin-top:3px}.return-link{display:block;width:fit-content;min-height:36px;padding:6px 0;border:0;border-radius:0;margin:6px 0 10px;font-size:12px;color:var(--blue);text-decoration:underline;text-underline-offset:3px}.return-link:hover{background:transparent}.ref-list .return-link{text-indent:0}
@media(max-width:760px){.top,main,footer{padding-left:20px;padding-right:20px}.intro h1{font-size:25px}.entry>summary{padding:15px 14px}.entry-body{padding:0 14px 16px}.catalog-heading{padding:18px 0;gap:12px}.group-note{font-size:12px}.group-choices{display:grid;grid-template-columns:1fr 1fr;gap:8px}.group-choices button{padding:8px 10px;font-size:12px}.exposure-snapshot{grid-template-columns:1fr}.practical p{font-size:14px}}
@media print{.return-link,.label-link{display:none}}
.evidence-list{margin:0;padding-left:19px;max-width:74ch}.evidence-list li{padding-left:3px}.evidence-list li+li{margin-top:12px}.practical .evidence-list{font-size:14px;line-height:1.65}.practical h3{margin-bottom:12px}
.reading .evidence-list{margin:10px 0 16px;padding-left:19px}.reading .evidence-list li+li{margin-top:15px}.evidence-result{display:block;margin-top:5px;font-variant-numeric:tabular-nums}.evidence-limit,.clinical .study-context{font-size:13px;line-height:1.6;color:var(--muted)}.product-context .evidence-list{font-size:13px}.evidence-list strong{font-variant-numeric:tabular-nums}
.product-exposure{border-top:1px solid var(--line);padding-top:16px;margin-top:14px;max-width:75ch}.product-exposure h3{font-size:14px;margin-bottom:12px}.product-exposure .supporting-body{padding-bottom:12px}.product-exposure .exposure-snapshot{margin:14px 0}.entry .product-exposure .evidence-action{margin-top:8px}.legacy-link{display:none}.legacy-link:target{display:block;margin-top:24px}.top nav a{min-height:44px;display:flex;align-items:center}.ref-list li:focus-visible{outline:2px solid var(--blue);outline-offset:2px}
.product-links{display:flex;flex-wrap:wrap;align-items:center;gap:0 24px;max-width:75ch;margin:0 0 12px}.product-links .label-link,.product-links .evidence-action{display:inline-flex;align-items:center;min-height:44px;padding:8px 0;margin:0;font-size:13px;font-weight:550}.product-links+.product-exposure{margin-top:0}.product-exposure .study-context{font-size:13px;color:var(--muted)}
.market-status{display:block;margin-top:6px;font-size:12px;font-weight:600;color:var(--muted)}
.group-advice{max-width:75ch;padding:0 0 20px;font-size:14px;line-height:1.65}
.group-advice .evidence-limit{margin-top:12px}
.group-advice .evidence-action{margin:8px 0 0;padding:8px 0;min-height:44px}
.entry-body>.supporting-body{padding-bottom:0}
.group-advice h3,.product-dose h3{font-size:14px;margin-bottom:10px}
.group-interactions{margin-top:20px}
.product-dose{max-width:75ch;border-top:1px solid var(--line);padding-top:16px;margin:16px 0 8px;font-size:13px;line-height:1.65}
.product-dose .dose-population{color:var(--muted);margin-top:9px}
.products-view{container:products / inline-size}
.products-view .group-choices{display:flex;flex-wrap:wrap;gap:8px}
.products-view .group-choices button{margin:0;padding:8px 16px;border-radius:24px;min-height:44px}
.product-tags{display:flex;flex-wrap:wrap;gap:6px;margin-top:8px}
.product-tag{display:inline-flex;padding:2px 8px;border:1px solid var(--line);border-radius:20px;background:var(--ground);font-size:11px;line-height:1.6;font-weight:550;color:var(--muted)}
.catalog-layout,#catalog,#guidance-home{min-width:0}
.catalog-guidance{border:1px solid var(--line);border-radius:12px;background:var(--surface);padding:20px;margin-bottom:20px}
.catalog-guidance h2{font-size:16px;line-height:1.35;margin-bottom:16px}
.catalog-guidance [data-guidance-topic]+[data-guidance-topic]:not([hidden]){margin-top:24px}
.catalog-guidance [data-guidance-topic][hidden]+[data-guidance-topic]{margin-top:0}
.catalog-guidance .group-advice{padding:0;font-size:13px}
.catalog-guidance .group-advice .evidence-action{margin-bottom:0;padding-bottom:0}
.entry-body>.catalog-guidance{background:var(--ground);margin-bottom:20px}
@container products (min-width:900px){
.catalog-layout[data-has-guidance="true"]{display:grid;grid-template-columns:minmax(0,1fr) 304px;gap:24px;align-items:start}
.catalog-layout>#catalog{grid-column:1;grid-row:1}
.catalog-layout>#guidance-home{grid-column:2;grid-row:1}
.catalog-guidance{margin-bottom:0}
}
@media(min-height:900px){
@container products (min-width:900px){#guidance-home{position:sticky;top:24px}}
}
@media print{.catalog-layout{display:block!important}#guidance-home{position:static}.catalog-guidance{break-inside:avoid}}